Modafinil is a wake-promoting agent that works by stimulating the brain’s sleep/wake pathways. It has been shown to reduce excessive daytime sleepiness in narcolepsy patients in controlled clinical trials.

It has also been used off-label as a cognitive enhancer in healthy individuals to increase alertness and improve performance on certain tasks. This use of the drug is controversial, and it should only be prescribed by a medical professional.

Narcolepsy

Buy Modafinil Online is a wake-promoting central nervous system stimulant that appears to act on areas of the brain involved in sleep/wake and biologic clock regulation. It increases activity without producing agitation and does not appear to affect the alpha1-adrenergic receptors. 

Modafinil is metabolized in part by the liver, so those with severe hepatic impairment should have their dose reduced. It is a reversible inhibitor of the enzyme CYP3A4, so concomitant use with 3A4 inducers, substrates or antagonists can affect concentrations of modafinil and its effect.

Those with narcolepsy are often very sleepy during the day and can experience trouble staying awake at night. They may also suffer from fragmented nighttime sleep, insomnia, vivid dreams and periodic leg movements during sleep.

Modafinil decreases the sleepiness associated with narcolepsy, but it does not cure the condition. People with narcolepsy should continue to follow their doctor’s advice for getting enough sleep, exercise, and using any breathing devices or other treatments that have been prescribed to them.

Shift Work Sleep Disorder

Working shifts is a practical necessity in many industries. But shifting work patterns can disrupt circadian rhythms and cause sleep problems. Studies show that up to one in five people who work shifts experience shift work disorder (SWSD).

SWSD results from disruption of your body’s internal clock, which is based on light and darkness. Light signals that you should wake up, while dark signals that it’s time to sleep. This pattern can cause difficulty falling asleep, waking up too early and poor performance on the job. It can also lead to mental and physical health issues, including depression, headaches and digestive problems.

Modalert 200 mg is a safe and effective stimulant drug that can help you stay awake during the day when you have SWSD or narcolepsy. It does not cure these conditions, but it can decrease symptoms and improve your quality of life. Your doctor may also prescribe other medications, such as a sleep aid, to help you fall asleep and stay asleep during the night.

Obstructive Sleep Apnea/Hypopnea Syndrome

Obstructive sleep apnea-hypopnea syndrome (OSAHS) is characterized by obstruction of the upper airway during sleep, resulting in repetitive breathing pauses and oxygen desaturation. This results in daytime sleepiness, a decreased quality of life, and can cause serious medical problems over time such as heart disease, stroke, high blood pressure, cognitive impairment and diabetes.

Hypopnea episodes are slowed or restricted breaths that occur in 10-second or longer 'episodes' repeatedly throughout the night. These can be obstructive, central or mixed obstructive-central and are often associated with sleep apnea.

Mild obstructive sleep apnea is often treated by weight loss, sleeping on the side instead of on the back, quitting smoking, avoiding alcohol and sedatives before bed, changing diet, or use of CPAP. Surgery is another option and can focus on the soft palate, uvula, tonsils, or adenoids, or can include more complex surgeries that adjust the upper jaw and facial bones. In cases where conservative treatments fail to improve symptoms, modafinil may be helpful in improving adherence to treatment and reducing the frequency of hypopnea events.

Cognitive Enhancement

Many people seek to enhance their cognition by taking drugs that have the potential to improve alertness and concentration. These drugs are known as cognitive enhancement substances (CES). This off-label use is popular with students and professionals who want to perform better in tests, interviews or other situations where their performance is assessed.

Modafinil is a non-amphetamine central nervous system stimulant and has wakefulness-promoting properties. It has been shown to improve attention for sleep-deprived individuals, but it does not seem to enhance planning, decision making or flexibility of thought, nor does it increase the ability to learn or recall information.

Using CES can cause serious or life-threatening side effects, such as Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis (TEN). People with certain health conditions should avoid modafinil, including people with hepatic or renal disease.

People with heart conditions should also avoid this drug, because it can worsen heart problems like mitral valve prolapse. Some prescription and nonprescription medicines can interact with modafinil, including omeprazole (Prilosec). Talk to your doctor or pharmacist before taking any other medications.